Tuesday, May 21, 2013

Sleepless Nights May Hurt School Performance of Kids With Asthma ...

teacher Sleepless Nights May Hurt School Performance of Kids With Asthma

TUESDAY, May 21 (HealthDay News) ? Urban elementary school children with poorly controlled asthma are likely to experience sleep problems and suffer academically, new research indicates.

?In our sample of urban schoolchildren, aged seven to nine, we found that compromised lung function corresponded with both poor sleep efficiency and impaired academic performance,? said study author Daphne Koinis-Mitchell, an associate professor of psychiatry and human behavior at Brown University?s Alpert Medical School in Providence, R.I.

Koinis-Mitchell, who is also an associate professor of pediatrics, is scheduled to present her findings Tuesday at the American Thoracic Society annual meeting in Philadelphia.

The findings stem from an analysis involving 170 pairs of white, black and Hispanic children and their fathers living in the Providence area.

The children?s asthma symptoms were monitored over three-month periods, and the children and their parents were asked to keep a health diary as well.

Questionnaires were also completed to gauge the degree to which asthmatic symptoms were kept under control. Sleep quality was also monitored and quantified.

The result: Children with poorly controlled asthma fared worse at school, according to their teachers. ?Carelessness? regarding school work was also linked to poorer sleep, as was difficulty in staying awake while in class.

?Urban and ethnic minority children are at an increased risk for high levels of asthma morbidity and frequent health care utilization due to asthma. Given the high level of asthma burden in these groups, and the effects that urban poverty can have on the home environments and the neighborhoods of urban families, it is important to identify modifiable targets for intervention,? Koinis-Mitchell said in a news release from the thoracic society.

Efforts aimed at improving asthma control and sleep quality may help to boost academic performance in this vulnerable population, she added. ?In addition, school-level interventions can involve identifying children with asthma who miss school often, appear sleepy and inattentive during class or who have difficulty with school work. Working collaboratively with the school system, as well as the child and family, may ultimately enhance the child?s asthma control,? she said.

Data and conclusions presented at meetings are typically considered preliminary until published in a peer-reviewed medical journal.

More information

For more on asthma and children, visit the American Lung Association.

HEALTHDAY Web XSmall Sleepless Nights May Hurt School Performance of Kids With Asthma

Source: http://news.health.com/2013/05/21/sleepless-nights-may-hurt-school-performance-of-kids-with-asthma/

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Bottom Line ? Regulatory Fairness Meeting for Small Business

On Thursday June 6, small business owners will have an opportunity to discuss issues regarding Federal regulatory compliance and enforcement. SBA Acting National Ombudsman Yolanda V. Swift will meet with members of the Seattle-area small business community to hear issues and comments about Federal regulatory enforcement and compliance actions.?Small business owners, representatives of trade associations, and community and business leaders are invited to participate, comment about compliance actions and enforcement of regulations by Federal agencies, and learn more about the impact of Federal regulations on small businesses.

This Seattle Hearing will be your opportunity to testify/discuss issues regarding Federal regulatory compliance and enforcement and how you have been affected as a small business owner. The SBA?s Office of the Ombudsman?s mission is?to assist small businesses when they experience excessive or unfair federal regulatory enforcement actions, such as repetitive audits or investigations, excessive fines, penalties, threats, retaliation or other unfair enforcement action by a federal agency.

The event will take place on Thursday, June 6 from 8:30 a.m. to 11:30 a.m. at the Rainier Club (820 4th Avenue, Seattle). To RSVP, contact Jose.Mendez@Seattle.gov.

The SBA?s Office of the Ombudsman also allows you to fill out a comment form on your experience working with Federal regulations. The comment form can be found here.

For more information or if you have any questions about this meeting, contact SBA Fairness Board Member Rich Gaspar at Rich@Gaspars.com

Source: http://bottomline.seattle.gov/2013/05/20/regulatory-fairness-meeting-for-small-business/

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Video Roundup: Science Friday Desktop Diaries

I don't have a desk, because there's no room in my apartment, but if I did it would probably be covered in so much crap that I wouldn't be able to use it anyway. And it makes me feel a little better to know that Nobel Prize-winning psychologist and economist Daniel Kahneman doesn't have a desk either.

I wouldn't know that, though, without the awesome Desktop Diaries series created by the team at Science Friday. They've been interviewing scientists about what's on their desks for more than a year and each video is a fascinating window into how these researchers work.

It's tough to pick a favorite when you can choose from Neil deGrasse Tyson showing off the Saturn-themed desk lamp he made in middle school, Michio Kaku pointing at imaginary dinosaurs in the corners of his office, Oliver Sacks playing with magnets, and Brian Greene talking about how he reformed his award-winning messiness, but Daniel Kahneman losing his Nobel Prize medal is certainly a contender for best moment. Spoiler: He eventually found it. [Science Friday]

Source: http://gizmodo.com/video-roundup-science-friday-desktop-diaries-508705841

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Pfizer halts study of non-Hodgkin's lymphoma drug

Drugmaker Pfizer Inc. has halted a late-stage study of an experimental cancer compound being tested in patients with a certain form of non-Hodgkin's lymphoma, because an interim analysis showed the drug wasn't helping patients live longer.

Pfizer said late Monday that it was stopping the study of its compound, inotuzumab ozogamicin, in patients who had relapsed after or not been helped by other treatments but who were not candidates for high-dose chemotherapy.

The patients in the study all had an aggressive form of non-Hodgkin's lymphoma in which cancerous white blood cells called B-cells had a substance on their surface called CD22. That substance is found in about 90 percent of cancers involving B-cells.

Inotuzumab ozogamicin combines a cell-killing agent with an antibody attracted to CD22. By binding to CD22, the compound can enter the B-cell. Once inside, the compound then releases the cell-killing agent, called calicheamicin, to destroy the cancerous B-cell.

In the study, half of the participants were given inotuzumab ozogamicin once a month, along with a standard cancer medicine, rituximab. The other half of patients were treated with rituximab and either of two other cancer drugs.

A planned analysis of results part way through the study showed patients getting rituximab and the experimental compound were not surviving any longer than the other patients.

Pfizer said the data did not turn up any new or unexpected safety problems with the experimental compound.

The New York-based company said it is continuing another late-stage study of the compound in adults who have relapsed after or haven't responded to treatment for a type of blood cancer called acute lymphoblastic leukemia.

"We are working to better understand the findings from this review to determine if there are any patterns of outcome that may help us gain greater understanding of the potential effect of inotuzumab ozogamicin in specific patient populations," Dr. Mace Rothenberg, head of clinical development and medical affairs for Pfizer's cancer business, said in a statement.

Rothenberg noted there are more than 70 types of cancers of the lymph system, blood and bone marrow that require unique treatments. He said Pfizer is committed to evaluating inotuzumab ozogamicin in patients with those cancers.

Cancer treatments are one of the priority research areas for Pfizer, the world's second-biggest drugmaker by revenue.

Last year, the company won approval for two targeted cancer drugs, Bosulif for advanced kidney cancer and Inlyta for certain patients with chronic myelogenous leukemia. It already sold Sutent, a blockbuster that treats multiple types of cancer.

Source: http://news.yahoo.com/pfizer-halts-study-non-hodgkins-223929428.html

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Galaxy S4 Mega, S4 Active and S4 Mini hinted in app update text

Galaxy S4 Mini, Mega, ActiveNew Samsung handsets outed in changelog for WatchON TV application

Rumors have been circulating for a few weeks that Samsung is working on a "Galaxy S4 Mini," as well as a ruggedized version of its current flagship device. Today an app changelog entry for the Galaxy S4's pre-loaded TV app could indicate that both are on the way, along with another device known as the "S4 Mega."

The shot above, sent our way by tipster Paul, shows that the recent 5.0.4 update for Samsung WatchON adds "support for [the] upcoming S4 Mega, S4 mini and S4 Active." The changelog has since been updated to remove the reference, suggesting that someone let the cat out of the bag a little early. The S4 Mini name has been rumored for some time, and the device is refers to extensively leaked. The S4 Active name would seem to refer to the rumored "waterproof" S4 variant. But the S4 Mega is a bit more of a mystery -- could the existing Galaxy Mega have been renamed? Or might this be a different large-screened S4 variant -- or simply a typo?

Whatever the case, the fact that WatchON has been updated with support for all three devices suggests that they'll likely include the S4's TV-controlling capabilities.

We'll have to wait and see if and when the Galaxy S4 Active, Mini and Mega emerge. Whatever form these handsets take, Samsung looks set to fully capitalize on the halo effect of its high-profile Galaxy S4 launch.

Thanks to Paul for tipping us the image above through the new Android Central app!

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/6KoK5XickOY/story01.htm

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Monday, May 20, 2013

Relay For Life Raises Thousands of Dollars for the American Cancer ...

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The Panama City Beach Relay for Life took place Friday night through Saturday Morning.

More than 200 people showed up throughout the night to rally for the cause.

The event was held at Arnold High School?s Gavlak Sports Complex and raised over 70 thousand dollars for the American Cancer Society.

30 local teams prepared for the event for months, and despite how exhausting the event can be, they say they are happy to support those who have been affected by cancer.

"The Relay for Life is one of the biggest fundraisers of any non-profit organization. Panama City Beach alone raised 70,000 dollars, Relay for Life as a whole has raised 4 billion dollars since 1985," said Brandon Greve, Relay for Life Event Chairman.

Source: http://www.wjhg.com/news/headlines/Relay-For-Life-Raises-More-Than-70-Thousand-Dollars-for-the-American-Cancer-Society-208052481.html

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Fossil brain teaser: New study reveals patterns of dinosaur brain development

May 20, 2013 ? A new study conducted at the University of Bristol and published online today in the Journal of Evolutionary Biology sheds light on how the brain and inner ear developed in dinosaurs.

Stephan Lautenschlager from Bristol's School of Earth Sciences, together with Tom H?bner from the Nieders?chsische Landesmuseum in Hannover, Germany, picked the brains of 150 million year old dinosaurs.

The two palaeontologists studied different fossils of the Jurassic dinosaur Dysalotosaurus lettowvorbecki: a very young (juvenile) individual of approximately three years of age and a fully grown specimen of more than 12 years of age.

Stephan Lautenschlager, lead author of the paper, said: "The two different growth stages of Dysalotosaurus provided a unique opportunity to study their brain, and how it developed during the growth of the animal."

Using high-resolution CT scanning and 3D computer imaging, it was possible to reconstruct and visualise the brain and inner ear of Dysalotosaurus lettowvorbecki -- a small, plant-eating dinosaur, which lived 150 million years ago, in what is now Tanzania.

Co-author Tom H?bner said: "Well-preserved fossil material, which can be used to reconstruct the brain anatomy is usually rare. Thus, we were fortunate to have different growth stages available for our study."

By looking at the brain and inner ear anatomy, the two researchers found that the brain of Dysalotosaurus underwent considerable changes during growth -- most likely as a response to environmental and metabolic requirements. However, important parts responsible for the sense of hearing and cognitive processes were already well developed in the young individual.

Stephan Lautenschlager said: "Our study shows that the brain was already well-developed in the young dinosaurs and adapted perfectly to interact with their environment and other individuals."

This study has important ramifications for the understanding of how parts of the brain developed in dinosaurs. However, further research into that field is necessary to investigate if the pattern of brain development in individual dinosaurs is also reflected in a large scale trend during the more than 150 million years of dinosaur evolution.

The study was funded by a research fellowship to Stephan Lautenschlager from the German Volkswagen Foundation.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/zFljwprhuAQ/130520114017.htm

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